Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Eukaryotic translation initiation factor 4E-binding protein 1' and Ligand = 'BDBM545293'
TargetEukaryotic translation initiation factor 4E-binding protein 1(Homo sapiens (Human))
eFFECTOR Therapeutics, Inc.

US Patent
LigandPNGBDBM545293(US11286268, Compound 781)
Show SMILES CN(C)C(=O)c1nc2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O
Show InChI InChI=1S/C29H23ClF3N5O5S/c1-13-9-17(25-22(34-13)18(12-44-25)28(41)42)16-10-15(30)5-6-21(16)43-8-7-38-14(2)35-20-11-19(29(31,32)33)23(26(39)37(3)4)36-24(20)27(38)40/h5-6,9-12H,7-8H2,1-4H3,(H,41,42)
Affinity DataIC50: 3.12nMAssay Description:eIF4E protein was pre-incubated with EDA-m7GDP-ATTO-550 in FPB at 2xconcentrations for 5 minutes prior to the addition of compounds. Compounds (100x)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid