Report error Found 12 Enz. Inhib. hit(s) with Target = 'Extracellular calcium-sensing receptor' and Ligand = 'BDBM50161093'
Affinity DataEC50: 41nMAssay Description:Inhibition of CaSR in bovine parathyroid cells assessed as increase in PTH levelMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.00300nMAssay Description:Displacement of [3H](2-(2-hydroxyphenyl)-6-methyl-5-(2-methylpropyl)-3-(2-phenylethyl)-4(3H)-pyrimidinone) from human calcium receptor expressed in h...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0580nMAssay Description:Antagonist activity at human calcium receptor expressed in HEK293 4.0-7 cells assessed as inhibition of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Antagonist activity at human CaSR expressed in rat PC12 cells transfected with zif promoter/luciferase by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human CaSR expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of intracellular calcium release in human TT cells containing calcium-sensing receptor by FLIPRMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Activity at rat CaSR in CHO cells assessed as inhibition of calcium ion-induced [3H]inositol phosphate accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of extracellular calcium-induced inositol triphosphate generation in rat MTC cells expressing calcium-sensing receptorMore data for this Ligand-Target Pair
