Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50426433'
TargetFatty acid synthase(Human)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426433(CHEMBL2322360)
Affinity DataIC50: 12nMAssay Description:Inhibition of FASN in human HeLa cells assessed as reduction of de novo synthesis of palmitateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426433(CHEMBL2322360)
Affinity DataIC50: 17nMAssay Description:Inhibition of human FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426433(CHEMBL2322360)
Affinity DataIC50: 22nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
Go to US Patent

TargetFatty acid synthase(Rat)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426433(CHEMBL2322360)
Affinity DataIC50: 62nMAssay Description:Inhibition of FASN in rat NMU cells assessed as reduction of de novo synthesis of palmitateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetFatty acid synthase(Rat)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426433(CHEMBL2322360)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed