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Found 13 Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 84' and Ligand = 'BDBM50239187'
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataKi:  1.78E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human GPR84 assessed as beta-arrestin recruitment by beta-galactosidase complementation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at human N-terminal-FLAG-tagged human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  6.08E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by beta-galactosidase complementation assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at human N-terminal FLAG-tagged GPR84 receptor stably expressed in CHO cells assessed as inhibition of forskolin-induced cAMP produc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.80E+4nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cells co-expressing Galpha16/Gqs5/Gqo5/Gqi9 assessed as increase in calcium mobilization...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  2.50E+4nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at recombinant human GPR84 expressed in HEK293 cells assessed as beta-arrestin 2 recruitment by beta-galactosidase based PathHunter ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.80E+4nMAssay Description:Agonist activity at human Gi1alpha-coupled GPR84 expressed in baculovirus infected Sf9 insect cells assessed as stimulation of [35S]GTPgammaS binding...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  3.00E+4nMAssay Description:Agonist activity at recombinant human N-terminally HA-tagged GPR84 expressed in CHO cells co-expressing Gqi5 assessed as inhibition of forskolin-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  7.42E+3nMAssay Description:Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50239187(CHEBI:30813 | Decanoic Acid | Decanoic Acid Anion)
Affinity DataEC50:  4.60E+3nMAssay Description:Agonist activity at human N-terminal FLAG-tagged GPR84 receptor stably expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS bind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed