Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [2420-3010]' and Ligand = 'BDBM243469'
TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243469(US9427440, 17)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent

TargetGenome polyprotein [2420-3010](HCV)
Janssen Ireland

US Patent
LigandPNGBDBM243469(US9427440, 17)
Affinity DataKon:  0.000160M-1s-1 Koff:  8.70E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
Go to US Patent