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Found 10 Enz. Inhib. hit(s) with Target = 'Glutamate receptor 4' and Ligand = 'BDBM17657'
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataKi:  354nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataKi:  868nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 4 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataKi:  868nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 4 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  2.80E+4nMAssay Description:Agonist activity at GluR4 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at rat recombinant GluR4 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonist activity at GluA4 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at GluA4 receptor (unknown origin) expressed in HEK293 cells assessed induction of S-glutamate-induced calcium flux measured after 9...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  2.00E+4nMAssay Description:Agonist activity at rat recombinant GluA4 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  1.96E+4nMAssay Description:Agonist activity at recombinant rat GluA4 receptor flip isoform expressed in Xenopus laevis oocytes by two-electrode voltage clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)
Affinity DataEC50:  1.70E+4nMAssay Description:Activity at rat cloned iGluR4 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed