Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 alpha' and Ligand = 'BDBM8296'
TargetGlycogen synthase kinase-3 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8296BDBM8296(CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...)
Affinity DataKi:  9nMAssay Description:Competitive inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8296BDBM8296(CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...)
Affinity DataKi:  9.10nM ΔG°:  -45.4kJ/mole IC50: 34.3nMpH: 7.0 T: 2°CAssay Description:In vitro kinase inhibition assay using purified GSK-3 alpha from insect cells, was incubated at room temperature with substrate, and test compounds i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8296BDBM8296(CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...)
Affinity DataIC50: 34nMAssay Description:Inhibition of GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8296BDBM8296(CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...)
Affinity DataIC50: 34nMAssay Description:Inhibition of full length recombinant human GSK-3alpha expressed in baculovirus infected insect Sf9 cells using GS-2 peptide as substrate assessed as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8296BDBM8296(CHEMBL102714 | cid_176158 | 3-(2,4-dichlorophenyl)...)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human GSK-3 alpha expressed in baculovirus infected Sf9 insect cells using GS-2 peptide after 30 mins in presence of [33P]g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed