Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with Target = 'Heat shock factor protein 1' and Ligand = 'BDBM50234078'
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  7nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  19nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  19nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSP72 induction preincubated for 1 hr followed by 17-AAG addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  22nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  40nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSPA1A mRNA level preincubated for 1 hr followed by 17-AAG ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234078(CHEMBL4087666 | US9701664, Example 63)
Affinity DataIC50:  40nMAssay Description:Inhibition of 17-AAG-induced HSF1 pathway in human SKOV3 cells assessed as reduction in HSPA1A mRNA level preincubated for 1 hr followed by 17-AAG ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed