Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50480379'
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 11nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 13nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 61nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50480379(SNX-5422 | CHEMBL553939)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed