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Found 2 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-alpha/90-beta' and Ligand = 'BDBM50485861'
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485861(chloroderivative)
Affinity DataIC50:  30nMAssay Description:Inhibition of human HSP90 using BODIPY labelled geldanamycin as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485861(chloroderivative)
Affinity DataIC50:  50nMAssay Description:Inhibition of human HSP90 in HCT116 cells expressing Her2 gene assessed as degradation of Her2 after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed