Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM50378702'
TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(SNX-2112 | CHEMBL560895)
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(SNX-2112 | CHEMBL560895)
Affinity DataIC50: 22nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(SNX-2112 | CHEMBL560895)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(SNX-2112 | CHEMBL560895)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed