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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM50379853'
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50: 4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50: 5nMAssay Description:Inhibition of HSP90 in human A375 cells assessed as induction of HSP70 synthesis after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50: 11nMAssay Description:Inhibition of HSP90-mediated pS6 phosphorylation in human A375 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Serenex

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50: 36nMAssay Description:Inhibition of HSP90-mediated Erk phosphorylation in human AU565 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed