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Found 4 Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50295750'
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295750(4-(6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295750(4-(6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-p...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295750(4-(6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-p...)
Affinity DataIC50:  820nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295750(4-(6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-p...)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of c-Met phosphorylation in human A549 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed