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Found 4 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3' and Ligand = 'BDBM139295'
TargetHistone deacetylase 3(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  158nMAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  218nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  218nMAssay Description:Inhibition of N-terminal GST-tagged HDAC3 (unknown origin) expressed in baculovirus expression system using FTS as substrate preincubated for 10 mins...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Regenacy Pharmaceuticals

US Patent
LigandPNGBDBM139295(US10858323, Compound 1 | US8614223, 73)
Affinity DataIC50:  219nMpH: 7.4 T: 2°CAssay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In DepthDetails US Patent