TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataKi: 0.990nMAssay Description:Inhibition of recombinant HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 0.420nMAssay Description:Inhibition of human HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of HDAC6 by in vitro deacetylation assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC6 assessed as blockade of decorboxylation of carboxyfluorescein labeled acetylated peptide substrate after 17 hrsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC6 (unknown origin) after 17 hrsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant HDAC6 expressed in Sf9 cells incubated for 2 hrs using RHKK-Ac fluorogenic substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human HDAC6 by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant HDAC6 using fluorophore-conjugated substrate Boc-L-Lys(Ac)-AMC after 60 minsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of mouse HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 16.8nMAssay Description:Displacement of fluorescent 5-(3-(3-(4-((4-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)phenylamino)methyl)-1H-1,2,3-triazol-1-yl)propyl)thioureido)-2-(3...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant histone deacetylase 6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human histone deacetylase 6 prepared from 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 28nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Mus musculus)
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against histone deacetylase 6 prepared from mouse melanoma B16/BL6 cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human HDAC6 using rhodamine as substrate after 1 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC6 by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
TargetHistone deacetylase 6(Mus musculus)
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 81nMpH: 8.0 T: 2°CAssay Description:The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 83.3nMAssay Description:Inhibition of human HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibitory concentration against histone deacetylase 6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
The Broad Institute Of Harvard And Mit
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of HDAC6 by fluorescence assayMore data for this Ligand-Target Pair