Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM294285'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM294285(US9586948, Example 4)
Show SMILES Cn1cc(NC(=O)c2cccc(n2)-c2ccnc(NC(=O)OC(C)(C)C)c2)c(n1)C(N)=O
Show InChI InChI=1S/C21H23N7O4/c1-21(2,3)32-20(31)26-16-10-12(8-9-23-16)13-6-5-7-14(24-13)19(30)25-15-11-28(4)27-17(15)18(22)29/h5-11H,1-4H3,(H2,22,29)(H,25,30)(H,23,26,31)
Affinity DataIC50: 785nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid