Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM294294'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM294294(US9586948, Example 13)
Show SMILES COc1cccc(c1)-c1cccc(n1)C(=O)Nc1cn(C)nc1C(N)=O
Show InChI InChI=1S/C18H17N5O3/c1-23-10-15(16(22-23)17(19)24)21-18(25)14-8-4-7-13(20-14)11-5-3-6-12(9-11)26-2/h3-10H,1-2H3,(H2,19,24)(H,21,25)
Affinity DataIC50: 637nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid