Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM294322'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM294322(US9586948, Example 41)
Show SMILES Cn1cc(NC(=O)c2cccc(n2)-c2ccnc(NCC3CC3)c2)c(n1)C(=O)N1CCOCC1
Show InChI InChI=1S/C24H27N7O3/c1-30-15-20(22(29-30)24(33)31-9-11-34-12-10-31)28-23(32)19-4-2-3-18(27-19)17-7-8-25-21(13-17)26-14-16-5-6-16/h2-4,7-8,13,15-16H,5-6,9-12,14H2,1H3,(H,25,26)(H,28,32)
Affinity DataIC50: 1.83E+3nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid