Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = 'Intestinal-type alkaline phosphatase' and Ligand = 'BDBM50241179'
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of IAP by analogous luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50:  2.02E+4nMAssay Description:Inhibition of human IAP using CDP-star as substrate pretreated for 10 mins followed by substrate addition measured after 10 mins by spectrophotometri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human IAP expressed in African green monkey COS7 cell membranes using CDP-star as substrate pretreated for 5 to 10 mins followed by sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of intestinal alkaline phosphatase (unknown origin) assessed as para nitrophenylphosphate conversion to p-nitrophenolate at pH 7.8 incubat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50: >4.00E+5nMpH: 7.8Assay Description:Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 7.8 followed by subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Bos taurus (Cattle))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50: >4.00E+5nMpH: 10.4Assay Description:Inhibition of bovine intestinal alkaline phosphatase using para-nitrophenylphosphate as substrate preincubated for 10 mins at pH 10.4 followed by sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntestinal-type alkaline phosphatase(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50241179((S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiaz...)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of intestinal alkaline phosphatase (unknown origin) assessed as para nitrophenylphosphate conversion to p-nitrophenolate at pH 10.4 incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed