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Found 2 Enz. Inhib. hit(s) with Target = 'Isoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM589754'
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50:  0.280nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50:  0.790nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent