Found 14 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50001714' TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
Affinity DataKi: 0.0200nMAssay Description:Binding affinity to human cloned kappa opioid receptor expressed in HEK293 cells by radioligand displacement assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
Affinity DataKi: 0.280nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
Affinity DataKi: 0.370nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297K mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
Affinity DataKi: 0.380nMAssay Description:Binding affinity using [3H]diprenorphine as the radioligand against E297A mutant Opioid receptor kappa 1 in COS-7 cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International
Curated by PDSP Ki Database
Sri International
Curated by PDSP Ki Database
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293T cell membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International
Curated by PDSP Ki Database
Sri International
Curated by PDSP Ki Database
Affinity DataIC50: 1.80nMAssay Description:Inhibition of opioid receptor kappa by displacing 0.5 nM [3H]bremazocine in guinea pig brain membraneMore data for this Ligand-Target Pair
Affinity DataKd: 0.0500nMAssay Description:Dissociation constant against E203Q,D204N,D206N EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.0380nMAssay Description:Dissociation constant against E203Q,D204N,D206N,E209Q EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKd: 0.0290nMAssay Description:Dissociation constant against wild type EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Pennsylvania
Curated by PDSP Ki Database
University Of Pennsylvania
Curated by PDSP Ki Database
Affinity DataKd: 1.10nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKd: 0.0500nMAssay Description:Dissociation constant against D216N,D217N,E218Q EL-2 Opioid receptor kappa 1 expressed in HEK cellsMore data for this Ligand-Target Pair
