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Found 5 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50346950'
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)
Affinity DataKi:  0.0600nMAssay Description:Mutant factor of the compound against mu-[K303E] with Opioid receptor kappa 1 for binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)
Affinity DataKi:  0.0900nMAssay Description:Effect on binding affinity of mutational exchange of Glu297 in the Opioid receptor kappa 1 in transiently expressed rat cos-7 cells activity expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)
Affinity DataKi:  0.150nMAssay Description:Displacement of [125I]-IBNtxA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]-IBNalA from KOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50346950(CHEMBL485832)
Affinity DataKi:  13nMAssay Description:Mutant factor of the compound against kappa[E297K] with Opioid receptor kappa 1 for binding affinity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed