Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50493818'
TargetKappa-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 assessed as increase in calcium mobilization incubated for 60 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed