Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Kelch-like ECH-associated protein 1' and Ligand = 'BDBM50130557'
TargetKelch-like ECH-associated protein 1(Human)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130557BDBM50130557(CHEMBL3632882)
Affinity DataIC50: 85nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction expressed in Escherichia coli BL21 codon plus cells using FITC-beta-DEETGEF-OH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130557BDBM50130557(CHEMBL3632882)
Affinity DataIC50: 400nMAssay Description:Binding affinity to the Keap1 (321 to 609 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by surface plasmon resonance assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50130557BDBM50130557(CHEMBL3632882)
Affinity DataKd:  400nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) protein-protein interaction by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed