Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Large neutral amino acids transporter small subunit 1' and Ligand = 'BDBM50219348'
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50219348((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
Affinity DataIC50:  8.50E+4nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLarge neutral amino acids transporter small subunit 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50219348((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
Affinity DataIC50:  8.70E+4nMAssay Description:Inhibition of human LAT1 expressed in HEK293-T-Rex cells assessed as inhibition of [3H]-gabapentin uptake by scintillation counting cis-inhibition as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed