Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Lysine-specific demethylase 5A' and Ligand = 'BDBM191596'
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM191596(6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of KDM5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM191596(6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of KDM5A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM191596(6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...)
Affinity DataIC50: 24nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5A(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM191596(6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...)
Affinity DataIC50: 24nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)