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Found 12 Enz. Inhib. hit(s) with Target = 'Lysine-specific histone demethylase 1A' and Ligand = 'BDBM283247'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMT: 2°CAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:To analyze LSD1 inhibitor efficacy in cells, a CD11b flow cytometry assay was performed. LSD1 inhibition induces CD11b expression in THP-1 (AML) cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD-1 demethylase activity. E. coli expressed full-length human LSD-1 (Accession numb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD-1 activity is based on Tnne Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM283247(4-[2-(4-aminopiperidyl)-1-methyl- 5-(1-methyl(1H-i...)
Affinity DataIC50: <100nMAssay Description:This assay determines the ability of a test compound to inhibit LSD1 demethylase activity. E. coli expressed full-length human LSD1 (Accession number...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent