Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50153209'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7TM Pharma A/S

Curated by ChEMBL
LigandPNGBDBM50153209(CHEMBL365055 | N-(2-Diethylamino-ethyl)-2-methoxy-...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1OC
Show InChI InChI=1S/C22H27F3N4O4/c1-4-29(5-2)13-12-26-20(30)18-11-8-16(14-19(18)32-3)28-21(31)27-15-6-9-17(10-7-15)33-22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)
Affinity DataIC50: 50nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligandMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7TM Pharma A/S

Curated by ChEMBL
LigandPNGBDBM50153209(CHEMBL365055 | N-(2-Diethylamino-ethyl)-2-methoxy-...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1OC
Show InChI InChI=1S/C22H27F3N4O4/c1-4-29(5-2)13-12-26-20(30)18-11-8-16(14-19(18)32-3)28-21(31)27-15-6-9-17(10-7-15)33-22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)
Affinity DataIC50: 150nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using scintillation proximity ass...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7TM Pharma A/S

Curated by ChEMBL
LigandPNGBDBM50153209(CHEMBL365055 | N-(2-Diethylamino-ethyl)-2-methoxy-...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)Nc2ccc(OC(F)(F)F)cc2)cc1OC
Show InChI InChI=1S/C22H27F3N4O4/c1-4-29(5-2)13-12-26-20(30)18-11-8-16(14-19(18)32-3)28-21(31)27-15-6-9-17(10-7-15)33-22(23,24)25/h6-11,14H,4-5,12-13H2,1-3H3,(H,26,30)(H2,27,28,31)
Affinity DataIC50: 260nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair