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Found 4 Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50172424'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172424(CHEMBL198361 | N-(4-Methyl-2-morpholin-4-yl-quinol...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of 15 pM [125I]-MCH from human MCH1R expressed in CHO-K1 in whole-cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172424(CHEMBL198361 | N-(4-Methyl-2-morpholin-4-yl-quinol...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against 10 nM MCH-induced IP3 accumulation in CHO-K1 cells expressing human MCH1R after incubation with [3H]-myo-inositolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172424(CHEMBL198361 | N-(4-Methyl-2-morpholin-4-yl-quinol...)
Affinity DataIC50:  50nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by SPA binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50172424(CHEMBL198361 | N-(4-Methyl-2-morpholin-4-yl-quinol...)
Affinity DataIC50:  82nMAssay Description:Displacement of 150p M [125I]-MCH from human MCH1R expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed