Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50381340'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy's Laboratories Ltd

Curated by ChEMBL
LigandPNGBDBM50381340(CHEMBL2016700)
Show SMILES Cc1nc(nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12)N1CCN(CC(C)(C)C)CC1
Show InChI InChI=1S/C26H32ClN5O2/c1-18-22-15-20(29-24(33)16-34-21-8-5-19(27)6-9-21)7-10-23(22)30-25(28-18)32-13-11-31(12-14-32)17-26(2,3)4/h5-10,15H,11-14,16-17H2,1-4H3,(H,29,33)
Affinity DataIC50: 246nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH peptide mediated response measuring [3H]inositol phosphate...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Dr. Reddy's Laboratories Ltd

Curated by ChEMBL
LigandPNGBDBM50381340(CHEMBL2016700)
Show SMILES Cc1nc(nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12)N1CCN(CC(C)(C)C)CC1
Show InChI InChI=1S/C26H32ClN5O2/c1-18-22-15-20(29-24(33)16-34-21-8-5-19(27)6-9-21)7-10-23(22)30-25(28-18)32-13-11-31(12-14-32)17-26(2,3)4/h5-10,15H,11-14,16-17H2,1-4H3,(H,29,33)
Affinity DataIC50: 782nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by SPA binding assayMore data for this Ligand-Target Pair