Found 32 Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50017181' 
Affinity DataKi: 0.300nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human recombinant MC4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Displacement of [125I]NDP-a-MSH from human recombinant MC4 receptor expressed in CHO cells measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]NDP-MSH binding to Melanocortin 4 receptor expressed in HEK293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of 125I-NDP-MSH from mouse MC4R expressed in HEK293 cells incubated for 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]-NDP-MSH from mouse melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]-NDP-MSH from mouse MC4R expressed in HEK293 cells after 1 hr by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Binding affinity for Human Melanocortin 4 receptor expressed in L-cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]-NDP-MSH from human melanocortin receptor 4 expressed in HEK293 cell mebranes incubated for 1 hr by automatic gamma counting me...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [I125]-NDP-MSH from wild type human melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0170nMAssay Description:Effective concentration required for the biological activity against human Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at human recombinant MC4 receptor expressed in BHK570 cells assessed as induction of cMAP accumulation in presence of 0.1% human ser...More data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Effective concentration required for intracellular cAMP accumulation by Melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Effective concentration for intracellular cAMP accumulation in human melanocortin 4 receptor expressing HEK 293 cells; (N = 4)More data for this Ligand-Target Pair
Affinity DataEC50: 0.460nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation incubated for 2 hrs by alphascreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.290nMAssay Description:Effective concentration for maximum agonist response towards mouse melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 0.390nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as increase in forskolin-induced cAMP accumulation preincubated for 2 hrs followed ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Agonist activity at mouse melanocortin 4 receptor expressed in HEK293 cells after 48 hrs by cAMP based beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.800nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as induction of cAMP accumulation after 2 hrs by alpha screen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.130nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.870nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.410nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as increase in cAMP accumulation after 2 hrs by AlphaScreen assa...More data for this Ligand-Target Pair
Affinity DataEC50: 6.40nMAssay Description:Agonist activity at EYFP-fused human MC4R expressed in HEK293 cells after 16 to 20 hrs by CRE-driven reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of intracellular cAMP accumulation incubated for ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at mouse melanocortin-4 receptor expressed in HEK293 cells co-transfected with CRE/beta-galactosidase reporter gene assessed as stim...More data for this Ligand-Target Pair
Affinity DataEC50: 0.279nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cAMP as...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at mouse melanocortin receptor 4 expressed in HEK293 cells assessed as stimulation of cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Agonist activity at mouse MC4R by alphascreen cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Activity at mouse MC4R expressed in HEK293 cells assessed as cAMP accumulation by CRE/beta-galactosidase reporter gene assayMore data for this Ligand-Target Pair
