Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with Target = 'Melatonin receptor type 1C' and Ligand = 'BDBM9019'
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.0794nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.176nMAssay Description:Effect of compound on Melatonin receptor in chicken brain in the presence of MnCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.460nMAssay Description:In vitro binding affinity against melatonin receptor using 2-[125I]iodomelatonin (0.05 nM) and chicken brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity towards melatonin receptor using 2-[125I]iodomelatonin as radioligand in chick brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2018
Entry Details

TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity towards melatonin receptor, determined in chicken brain membranes using [2-125I]melatoninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.590nMAssay Description:Displacement of 2-[125I]iodomelatonin from chick brain melatonin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity in chicken brain membranes by using [2-125I]melatonin in a competition radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity towards melatonin receptor in chicken brain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.590nMAssay Description:Binding affinity towards melatonin receptor was determined using 2-[125I]iodomelatonin as radioligand in chick brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2018
Entry Details

TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.670nMAssay Description:Competitive binding by the displacement of 2-[125I]- Iodomelatonin binding from melatonin receptors in chicken brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.676nMAssay Description:Binding affinity against chicken brain melatonin receptors using 2-[125I]iodomelatonin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of 2-[125I]- iodomelatonin from chicken brain melatonin receptorsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  1.10nMAssay Description:Effect of compound on Melatonin receptor in chicken brain in the presence of GTP-gamma-SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  1.86nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  1.87nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(Chicken)
Cnrs-Biocis

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9019BDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  23nMAssay Description:Functional activity against melatonin receptor in lightening Xenopus laevis tadpole skinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed