Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50007548'
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50: >1.00E+5nMAssay Description:Metabotropic glutamate receptor 1 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50: >1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1c in ratMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50:  1.00E+6nMAssay Description:Effect on Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat mGluR1 by measuring intracellular calcium concentration in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat recombinant mGluR1 expressed in CHO cells assessed as intracellular calcium concentrationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of binding to rat mGluR1a (metabotropic glutamate receptor) expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50007548(2-Amino-4-phosphono-butyric acid | 2-amino-4-phosp...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]Quisqualate from human mGluR1A receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed