Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50128099'
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128099(CHEMBL3628083)
Show SMILES Clc1cc(NC(=O)c2ccc[nH]2)ccc1N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C19H12ClN3O3/c20-14-10-11(22-17(24)15-6-3-9-21-15)7-8-16(14)23-18(25)12-4-1-2-5-13(12)19(23)26/h1-10,21H,(H,22,24)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50128099(CHEMBL3628083)
Show SMILES Clc1cc(NC(=O)c2ccc[nH]2)ccc1N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C19H12ClN3O3/c20-14-10-11(22-17(24)15-6-3-9-21-15)7-8-16(14)23-18(25)12-4-1-2-5-13(12)19(23)26/h1-10,21H,(H,22,24)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...More data for this Ligand-Target Pair