Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50204261'
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204261(CHEMBL3969063)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells co-expressing human EAAT1 assessed as reduction of DCG-4-inhi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50204261(CHEMBL3969063)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed