Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50434132'
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50434132(CHEMBL2381642)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human mGlu2 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50434132(CHEMBL2381642)
Affinity DataIC50: 8.60nMAssay Description:Agonist activity at mGlu2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50434132(CHEMBL2381642)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2018
Entry Details Article
PubMed