Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 1' and Ligand = 'BDBM35646'
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35646(erk000506 | pyrimidylpyrrole, 9e)
Affinity DataKi:  4nM ΔG°:  -48.7kJ/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by kinase was converted to ATP with the concomitant production of pyruvate from PE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35646(erk000506 | pyrimidylpyrrole, 9e)
Affinity DataKi:  4nMAssay Description:Assay 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM35646(erk000506 | pyrimidylpyrrole, 9e)
Affinity DataKi:  4nMAssay Description:Photometric_Method2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R