Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM14838'
TargetMitogen-activated protein kinase 14(Mouse)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM14838(CHEMBL105248 | BIRB-796 Analog 32 | 1-(5-iso-Propy...)
Affinity DataKd:  6nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM14838(CHEMBL105248 | BIRB-796 Analog 32 | 1-(5-iso-Propy...)
Affinity DataKd:  3.40nMpH: 7.0 T: 2°CAssay Description:UV thermal melt experiments were carried out in a quartz cuvette loaded with sample containing enzyme and each test compound using a spectrophotomete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14838(CHEMBL105248 | BIRB-796 Analog 32 | 1-(5-iso-Propy...)
Affinity DataKon:  0.000380M-1s-1Assay Description:Rate of dissociation from Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14838(CHEMBL105248 | BIRB-796 Analog 32 | 1-(5-iso-Propy...)
Affinity DataKd:  5.90nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14838(CHEMBL105248 | BIRB-796 Analog 32 | 1-(5-iso-Propy...)
Affinity DataKon:  0.000380M-1s-1 Koff:  6.48E+4s-1Assay Description:Rate of dissociation from Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed