Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 14' and Ligand = 'BDBM14844'
TargetMitogen-activated protein kinase 14(Mouse)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM14844(3-[3-tert-butyl-1-(6-methylpyridin-3-yl)-1H-pyrazo...)
Affinity DataKd:  0.180nMpH: 7.0 T: 2°CAssay Description:UV thermal melt experiments were carried out in a quartz cuvette loaded with sample containing enzyme and each test compound using a spectrophotomete...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14844(3-[3-tert-butyl-1-(6-methylpyridin-3-yl)-1H-pyrazo...)
Affinity DataKon:  0.0000230M-1s-1 Koff:  2.15E+4s-1Assay Description:Rate of dissociation from Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14844(3-[3-tert-butyl-1-(6-methylpyridin-3-yl)-1H-pyrazo...)
Affinity DataKon:  0.0000230M-1s-1Assay Description:Rate of dissociation from Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM14844(3-[3-tert-butyl-1-(6-methylpyridin-3-yl)-1H-pyrazo...)
Affinity DataKd:  1.10nMAssay Description:Binding affinity for Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed