Found 7 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50364378'
Affinity DataKi: 44nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 133nMAssay Description:Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-labeled 4EBP1 peptide measured after 1 hr by time-resolved fluores...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of JNK1 in mouse RAW264.7 cells assessed as inhibition of c-Jun phosphorylation incubated for 30 mins by cellular assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of c-Jun phosphorylation in LPS-stimulated JNK1-/- mouse embryonic fibroblast incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of c-Jun phosphorylation in LPS-stimulated JNK2-/- mouse embryonic fibroblast incubated for 30 mins by ELISAMore data for this Ligand-Target Pair