Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 14' and Ligand = 'BDBM158770'
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM158770(US9034866, 245)
Affinity DataKi:  620nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM158770(US9034866, 245)
Affinity DataKi:  1.00E+3nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM158770(US9034866, 245)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of NIK (unknown origin) after 1 to 2 hrs by ADP-FP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed