Affinity DataKi: 0.230nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 0.562nMAssay Description:Displacement of [3H]DPN from human recombinant mu-type opioid receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.660nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
Memorial Sloan-Kettering Cancer Center
Curated by PDSP Ki Database
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 0.680nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 0.680nMAssay Description:Affinity to mu-receptor, using [3H]DAMGO as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as inhibition of DAGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 0.980nMAssay Description:Binding affinity to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to mu-opioid receptor (unknown origin)More data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]-Naloxone (0.5 nM)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of 2-((1E,3E,5E)-5-(1-Ethyl-3,3-dimethyl-5-sulfoindolin-2-ylidene)-penta-1,3-dien-1-yl)-1-(6-((6-((6S,7R,7aR,12bS)-9-hydroxy-7-methoxy-3...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 1.10nMAssay Description:Displacement [3H]-naloxone from the Opioid receptor mu 1 isolated from rat brain membrane.More data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells preincubated for 1 hr followed by radioligand addition measured after 1 hr by liqu...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 1.40nMAssay Description:Inhibition of [3H]-DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DAGO from mu opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-naloxone from human mu opioid receptor expressed in CHO-K1 cells by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-DAMGO from MOR in guinea pig brain membranes measured by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Institut F£R Pharmazeutische Und Medizinische Chemie
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:In vitro binding affinity to human Opioid receptor mu 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [3H]diprenorphine from human cloned mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 3.70nMAssay Description:Binding affinity towards mu opioid receptor by displacement of [3H]-NAL from rat brain homogenatesMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 3.70nMAssay Description:Tested for binding affinity towards mu receptor in presence of [3H]-NAL radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Antagonist activity against human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of loperamide-stimulated [35S]GTP-gamma-S b...More data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of binding of the non-selective opioid antagonist, [3H]diprenorphine, to cloned human mu opioid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [125I]-IBNtxA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
R. W. Johnson Pharmaceutical Research Institute
Curated by PDSP Ki Database
Affinity DataKi: 6.30nMAssay Description:Binding affinity towards mu-opioid receptor by the displacement of [3H]-Nal in rat brain homogenatesMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [3H]diprenorphine human MOR expressed in CHO cell membranes after 1 hr by micro beta2 scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-diprenorphine from human MOR expressed in CHO cell membranes incubated for 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by micro beta2 scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
Affinity DataKi: 354nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair