Found 9 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50474150' TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.0100nMAssay Description:Binding affinity to mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.0871nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 0.282nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of DAMGO-induced beta-arrestin-2 recruitment at mu opioid receptor-1 (unknown origin) expressed in CHO cells preincubated for 30 mins foll...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DPDPE by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at mouse mu opioid receptor-1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding incubated for 60 mins by scintillat...More data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Inhibition of mu opioid receptor (unknown origin) in presence of DAMGO by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
