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Found 13 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50474153'
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  7.20nMAssay Description:Inhibition of mu opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  7.20nMAssay Description:Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in HEK293 cell membranes incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  9.80nMAssay Description:Displacement of [3H]DAMGO from guinea pig brain mu opoid receptor after 3 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  13nMAssay Description:Binding affinity using guinea pig brain membrane preparations, towards Opioid receptor mu 1 using [3H]- DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]DAMGO from mu opoid receptor in Dunkin-Hartley guinea pig brain after 1.5 hrs by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataKi:  37nMAssay Description:Displacement of [125I]-IBNtxA from mouse mu opioid receptor-1 expressed in CHO cell membranes incubated for 90 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataIC50:  725nMAssay Description:Inhibition of DAMGO-induced beta-arrestin-2 recruitment at mu opioid receptor-1 (unknown origin) expressed in CHO cells preincubated for 30 mins foll...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  5.90nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  53nMAssay Description:Agonist activity at mu opioid receptor in guinea pig brain membranes by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  5.93nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells assessed as stimulation of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  7.60nMAssay Description:Agonist activity at human recombinant mu opioid receptor expressed in CHO cells assessed as stimulation of cAMP accumulation incubated for 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Memorial Sloan Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50474153(CHEMBL61630)
Affinity DataEC50:  53nMAssay Description:Agonist activity at mouse mu opioid receptor-1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding incubated for 60 mins by scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed