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Found 5 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50580195'
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580195(CHEMBL5071286)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor (unknown origin) expressed in CHO cells at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580195(CHEMBL5071286)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580195(CHEMBL5071286)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at human MOR receptor expressed in HTLA cells co-expressing TEV-fused-beta-arrestin2 assessed as induction of beta-arrestin2 recruit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580195(CHEMBL5071286)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at human MOR expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulation incubated for 30 mins by Gl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Health Sciences & Pharmacy At St. Louis

Curated by ChEMBL
LigandPNGBDBM50580195(CHEMBL5071286)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at human MOR receptor expressed in HTLA cells co-expressing TEV-fused-beta-arrestin2 assessed as induction of beta-arrestin2 recruit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed