Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50122054'
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122054BDBM50122054(N-desmethyl-Clozapine | 8-Chloro-11-piperazin-1-yl...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human muscarinic M1 receptor expressed in CHO-K1 cells assessed as increase of acetylcholine-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122054BDBM50122054(N-desmethyl-Clozapine | 8-Chloro-11-piperazin-1-yl...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at muscarinic M1 receptor (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50122054BDBM50122054(N-desmethyl-Clozapine | 8-Chloro-11-piperazin-1-yl...)
Affinity DataKi:  60.3nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed