Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50401040'
TargetMuscarinic acetylcholine receptor M1(Human)
University of Strasburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401040BDBM50401040(CHEMBL2206333)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as inhibition of carbachol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Strasburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401040BDBM50401040(CHEMBL2206333)
Affinity DataKd:  794nMAssay Description:Binding affinity to EGFP-fused human muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Strasburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401040BDBM50401040(CHEMBL2206333)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells after 22 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
University of Strasburg

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50401040BDBM50401040(CHEMBL2206333)
Affinity DataEC50:  2.51E+4nMAssay Description:Displacement of [3H]NMS from EGFP-fused human M1 receptor N-terminal truncated at 17 residues expressed in HEK293 cells assessed as reduction of [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed