Found 2 Enz. Inhib. hit(s) with Target = 'NACHT, LRR and PYD domains-containing protein 3' and Ligand = 'BDBM50538420' TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare
Curated by ChEMBL
Cadila Healthcare
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
Cadila Healthcare
Curated by ChEMBL
Cadila Healthcare
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in TNF alpha level preincubated for 1 hr followed by...More data for this Ligand-Target Pair
