Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Neuromedin-K receptor' and Ligand = 'BDBM50341112'
TargetNeuromedin-K receptor(Homo sapiens (Human))
Euroscreen SA

Curated by ChEMBL
LigandPNGBDBM50341112((4-(2-methoxyphenyl)piperazin-1-yl)(3-(pyridin-4-y...)
Show SMILES COc1ccccc1N1CCN(CC1)C(=O)c1cc(n[nH]1)-c1ccncc1
Show InChI InChI=1S/C20H21N5O2/c1-27-19-5-3-2-4-18(19)24-10-12-25(13-11-24)20(26)17-14-16(22-23-17)15-6-8-21-9-7-15/h2-9,14H,10-13H2,1H3,(H,22,23)
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at human recombinant NK3 receptor expressed in CHO cells assessed as inhibition of NKB-induced increase of intracellular calcium ...More data for this Ligand-Target Pair