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Report error Found 3 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor subunit alpha-4' and Ligand = 'BDBM50088453'
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088453(CHEMBL72433 | NS3570, 5 | 1-(6-bromo-5-ethoxypyrid...)
Affinity DataEC50:  257nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in HEK293 cells assessed as intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50088453(CHEMBL72433 | NS3570, 5 | 1-(6-bromo-5-ethoxypyrid...)
Affinity DataIC50: 0.871nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
University of Copenhagen

LigandPNGBDBM50088453(CHEMBL72433 | NS3570, 5 | 1-(6-bromo-5-ethoxypyrid...)
Affinity DataKi:  0.25nMAssay Description:Binding affinities for alpha 4 beta 2 nAChR were determined in tissue suspension of rat cortical membranes using 1 nM [3H]cytisine. Binding affiniti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed